Variable selection and specification of robust QSAR models from multicollinear data: arylpiperazinyl derivatives with affinity and selectivity for α2-adrenoceptors

Abstract  Two QSAR models have been identified that predict the affinity and selectivity of arylpiperazinyl derivatives for 1 and 2 adrenoceptors (ARs). The models have been specified and validated using 108 compounds whose structures and inhibi